View Summary
“New Leadership, vision for the Worldwide Innovative Network Consortium in Precision Oncology” View Summary

WINning together

WIN was formed on the premise that we can accomplish more together than each organization can achieve working alone. We aim to improve cancer patients’ survival and quality of life. View WIN's history and unique attributes:

WIN represents a global collaboration of cancer centers, life science and biotech organizations, and technology companies and not-for-profit organizations.
The Worldwide Innovative Networking (WIN) Consortium in personalized cancer medicine was initiated in 2010 with leadership from leading cancer centers worldwide. WIN is a non-profit, non-governmental organization headquartered in Paris.

WIN was created to accelerate the pace and reduce the cost of translating novel cancer treatments to the bedside by developing and applying, through worldwide clinical trials and research projects, the most promising advances in genomic-based cancer research. WIN aims to initiate research projects each year in a global consortium guided by an independent scientific advisory board.

WIN now includes 27 institutional members. These stakeholders have come together from all parts of the world to address the challenge of increasing the efficacy of cancer diagnostics and therapeutics by understanding the genetics and biology of each individual’s tumor and accounting for genetic differences across diverse populations—from North and South America, Europe, Asia, Middle East and Australia.

Our goal is to significantly improve outcomes for patients around the globe. We aim to increase the number of patients worldwide that have access to innovative, global clinical trials in the area of genomic-based cancer therapeutics. Global diversity and inclusion of all stakeholders is WIN’s most important and differentiating asset.
WIN is comprised of organizations representing all stakeholders in personalized cancer medicine.
WIN enables cross-sector collaborations designed to accelerate the speed and efficacy with which breakthroughs in personalized cancer medicine can be realized and brought to patients worldwide.

Our members include leading academic, life science, not-for-profit, health, patient advocacy and IT organizations.
Our members include 22 leading academic centers representing 18 countries and five continents, enabling coordinated studies with a global patient population.
The response to a genetically-targeted therapy can vary due to differences in ethnicity and environment. WIN's global studies are designed to identify and account for this variability, enhancing the speed and efficacy with which novel discoveries can be made and brought to patients around the world.

WIN prioritizes cross-sector interaction designed to enhance learning across and between continents and healthcare sectors.
WIN Symposia, held annually, brings together hundreds of leaders representing all stakeholders from around the world in a forum designed to promote the exchange of ideas and information.

Clinical trials, projects and publications

WIN members collaboratively design and carry out global studies designed to achieve breakthroughs for patients worldwide. Our distinguished Scientific Advisory Board oversees WIN studies. Current trials include:

“Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival”
WIN's article “Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival” published by NPJ Precision Oncology, a Nature Research journal.
SPRING 01 (Survival Prolongation by Rationale Innovative Genomics) proof of concept trial is the first trial exploring the tri-therapy strategy in first line of advanced/metastatic non-small cell lung cancer (NSCLC), following the historical success of this approach in AIDS and tuberculosis for which only tri-therapy demonstrated long term efficacy.
The WIN SPRING trial was conducted in the USA, France, Spain, Luxembourg and Israel in the following cancer centers: University of California - San Diego's Moores Cancer Center, Avera Cancer Center (Sioux Falls, Arizona), Institut Curie (Paris), Centre Léon Bérard (Lyon), Vall d'Hebron Institute of Oncology (Barcelona), Centre Hospitalier de Luxembourg (Luxembourg), and Chaim Sheba Medical Center (Israel).

The trial was sponsored by the WIN Consortium and funded by ARC Fondation for cancer research (France). The drugs were donated by Pfizer Inc.
Published in Nature Medicine, results of WINTHER, the first study pioneered by the WIN Consortium.
Published in Nature Medicine, results of WINTHER, the first study pioneered by the WIN Consortium.

Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial - shows that RNA profiling together with DNA testing matches more patients with advanced cancer to personalized therapies than DNA profiling for tumor mutations alone.

WIN is currently planning innovative global clinical trials that represent the next generation of studies focused on lung cancer.
European funded trials WINTHER EU FP7 funded and CHEMORES EU FP6 funded established foundations for WIN future global strategy for lung cancer currently under development.

The concept underlying the new strategy is developed in the following publications:

People leadership

WIN leaders are selected for their contributions and commitment to making effective, personalized cancer medicine a reality for patients around the world. They guide WIN's strategic, operational, and scientific direction.

Organization Photo

Organization

The WIN Consortium is organized in the following groups who collectively work together to achieve WIN's common goals

Wafik El-Deiry Photo
Chair, WIN Consortium
Wafik El-Deiry

Chair, WIN Consortium; Director, Legorreta Cancer Center at Brown University (USA)

Richard L. Schilsky Photo
Chair Emeritus, WIN Consortium
Richard L. Schilsky

Chair Emeritus, WIN Consortium; Professor Emeritus, University of Chicago; past President and former Executive Vice President & Chief Medical Officer (ASCO) (USA)

Razelle Kurzrock Photo
Chief Medical Officer, Executive Committee, Equal Opportunity and Diversity Officer, WIN Consortium
Razelle Kurzrock

Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director Clinical Research, MCW Cancer Center and Linda T. & John A. Mellowes of Precision Oncology (USA)

Catherine Bresson Photo
Director, Operational Team, WIN Consortium
Catherine Bresson

Director, Operational Team, WIN Consortium


Our members and collaborators

WIN members include 37 leading organizations representing all stakeholders in personalized cancer medicine covering 20 countries and 4 continents. Our shared vision is delivering the promise of effective, personalized cancer medicine to patients worldwide. The WIN Consortium has collaborated with additional academic institutions and pharmaceutical partners in successful completion of global clinical trials in precision oncology.


WIN Symposia

WIN Symposia, held annually, gathers leaders representing a breadth of stakeholders from around the world to learn, share, and collaborate. Our latest symposium took place in Abu Dhabi, UAE, for further information, visit: win-burjeel-symposium.com/

Abstracts Presented at the 2024 WIN Symposium in Partnership with Burjeel Holdings March 1-2, 2024, Abu Dhabi, United Arab Emirates logotype

Abstracts Presented at the 2024 WIN Symposium in Partnership with Burjeel Holdings March 1-2, 2024, Abu Dhabi, United Arab Emirates

March 01, 2024 - March 02, 2024

The WIN Symposium 2024, a landmark event in precision oncology, took place in Abu Dhabi, United Arab Emirates (UAE), on the 1st and 2nd of March 2024; marking a significant collaboration between the Worldwide Innovative Network (WIN) Consortium and Burjeel Holdings. This annual global congress of the WIN Consortium brought together physicians, researchers, and scientists from 30 countries to explore the latest advancements in precision oncology, with the ultimate goal of improving cancer patient care and outcomes worldwide.
The call for abstracts attracted 51 submissions with 42 accepted as posters and 3 as oral presentations. This publication features 34 of the accepted abstracts.

The abstracts are now published online on the JIPO website:
https://meridian.allenpress.com/innovationsjournals-JIPO/article/doi/10.36401/JIPO-24-X2/500828/Abstracts-Presented-at-the-2024-WIN-Symposium-in
or can be downloaded from this section.

WIN 2024 Symposium logotype

WIN 2024 Symposium

March 01, 2024 - March 02, 2024

The two-day WIN Symposium 2024, organized by the WIN Consortium and hosted by Burjeel Holdings took place in Abu Dhabi, United Arab Emirates on 1-2 March 2024.

Under the theme of “Precision and Molecular Oncology: Caring for Patients and Future Generations,” the symposium brought together more than 450 expert clinicians, researchers and industry professionals from over 30 countries. Together, they explored the latest advances in precision oncology and offered insights into the developments shaping the future of oncology. The symposium started with an inspiring keynote lecture by Nobel Laureate Professor James Allison, who has revolutionized cancer immunotherapy. The curated programs featured interactive elements illustrating precision cancer treatment principles and best practices.

More than 50 abstracts were received from over 15 countries. The event was endorsed by the American Society of Clinical Oncology (ASCO®) and accredited for 8.5 European CME credits (ECMEC®s) by the European Accreditation Council for Continuing Medical Education (EACCME®).

The WIN Symposium provided attendees with a deep understanding of the role of key biomarkers, their optimal application, and emerging new omic tests that will inform future biomarker adoption under the two big umbrellas of Precision Genomics and Precision Immunotherapy. Local experience from the UAE, the host country, was included to link global evidence to regional practice. Application of the principles of precision medicine were discussed beyond medical and onto radiation oncology along with issues of access, equity and diversity in precision oncology practice and trials on a global scale. The symposium featured a Molecular Tumor Board to exemplify with real patient cases how to use biomarkers to inform therapeutic choices. Finally, a panel discussion was dedicated to navigating available diagnostic pathways and tests from bench to bedside.

The symposium provided networking opportunities, allowing participants to connect with peers, establish collaborations, and forge new partnerships.

Visit our dedicated symposium website for all the details of this event: https://win-burjeel-symposium.com/.

ASCO® is a registered trademark of the American Society of Clinical Oncology®. Used with permission. This is not an ASCO sponsored event.

WIN 2022 Symposium logotype

WIN 2022 Symposium

October 29, 2022 - October 30, 2022

The WIN 2022 Symposium ‘Integrating Genomics and Transcriptomics to Reshape Precision Oncology: A WINning Strategy’ took place on 29-30 October, 2022 in Barcelona, Spain.

We had an exciting line-up of prominent speakers and panel discussion and our 1st international molecular board!

 


What people are saying

What people are saying
I am looking forward to expanding further the WIN membership with world-class cancer centers as well as diagnostics, biotech, and pharma companies. WIN represents a fabulous platform to launch compelling precision oncology and early diagnosis studies internationally building upon our experience in genomics and transcriptomics. We are looking forward to entering into partnership with drugs and omics companies as well as philanthropy to pursue our common objective to insure that all patients have access to precision cancer care and research studies. Wafik El-Deiry, WIN Chair
play
What people are saying
"WIN is an unique, global, translational clinical research organization with a bold vision to bring cutting edge science and technology to the cure of cancer worldwide. It is a privilege to help guide the organization as Chair Emeritus." Richard L. Schilsky, WIN Chair Emeritus
What people are saying
"Achieving much needed major clinical breakthroughs in cancer treatment requires bold thinking and action, a can do attitude and winning spirit, and close collaboration of stakeholders and contributors with diverse background and expertise. All this is epitomized by WIN." Vladimir Lazar, Chief Scientific and Operating Officer
What people are saying
Exploring Precision Oncology - Interview with Dr. Razelle Kurzrock, Chief Medical Officer and Dr. Sewanti Limaye at WIN 2022 Symposium  (To view the video, scroll through this slider or go to the News section) JIPO and WIN Consortium
play

October 10, 2024 - Rutgers Cancer Institute and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium have joined forces to advance innovative cancer research
October 10, 2024 - Rutgers Cancer Institute and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium have joined forces to advance innovative cancer research

“We are very proud to welcome Rutgers Cancer Institute to WIN,” said Dr. Wafik S. El-Deiry, Chair of WIN Consortium, and Director, Legorreta Cancer Center, Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University, “Rutgers Cancer Institute together with RWJBarnabas Health is one of an elite group of National Cancer Institute (NCI)-Designated Comprehensive Cancer Centers and the only one in the state of New Jersey. This coveted designation gives Rutgers Cancer Institute the distinction of being among the best cancer research institutions in the U.S. Rutgers Cancer Institute has amazing colleagues who we are excited to collaborate with through innovative next-generation precision oncology trials.”

WIN was the first consortium that assembled all stakeholders of cancer care, from academia, industry, and patient advocates to work together across the globe. It was also the first organization to launch a N-of-One study using transcriptomics in addition to genomics to inform therapeutic choice in the WINTHER study. “It is with great excitement that we at WIN welcome Rutgers Cancer Institute, which is a leading cancer institution, and its talented faculty,” said Dr Razelle Kurzrock, Chief Medical Officer of WIN, Professor of Medicine, Associate Director Clinical Research, MCW Cancer Center and Linda T. & John A. Mellowes of Precision Oncology.

“Joining the global WIN Consortium strengthens our mission to improve cancer outcomes worldwide,” said Dr. Steven K. Libutti, Director, Rutgers Cancer Institute and Senior Vice President, Oncology Services, RWJBarnabas Health. “This partnership allows us to collaborate on cutting-edge research and leverage the expertise of leaders in the field, all aimed at delivering more personalized and elective cancer care. With the Jack and Sheryl Morris Cancer Center opening in 2025, we are even better positioned to innovate and enhance treatment for our patients.”

View the full article here: Download pdf
October 09, 2024 - Atrium Health Wake Forest Baptist’s Comprehensive Cancer Center and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium have joined forces to advance innovative cancer research.
October 09, 2024 - Atrium Health Wake Forest Baptist’s Comprehensive Cancer Center and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium have joined forces to advance innovative cancer research.
“We are very proud and excited to welcome Atrium Health Wake Forest Baptist’s NCI-Designated Comprehensive Cancer Center to WIN,” said Dr. Wafik S. El-Deiry, Chair of WIN Consortium, and Director, Legorreta Cancer Center, Associate Dean, Oncologic Sciences, Warren Alpert Medical School, Brown University.

WIN was the first consortium that assembled all stakeholders of cancer care, from academia, industry, and patient advocates to work together across the globe. It was also the first organization to launch a N-of-One study using transcriptomics in addition to genomics to inform therapeutic choice in the WINTHER study. “We are looking forward to working with amazing colleagues from Atrium Health Wake Forest Baptist’s Comprehensive Cancer Center on innovative next-generation precision oncology trials,” said Dr Razelle Kurzrock, Chief Medical Officer of WIN, Professor of Medicine, Associate Director Clinical Research, MCW Cancer Center and Linda T. & John A. Mellowes of Precision Oncology.
“Defeating cancer is a team sport, and I am so delighted that our Atrium Health Wake Forest Baptist Comprehensive Cancer Center team is able to leverage our role, along with Atrium Health Levine Cancer, as the largest provider of cancer care in the Southeast USA to the important shared efforts of the WIN Consortium,” said Dr. Ruben A. Mesa, Executive Director, Atrium Health Wake Forest Baptist Comprehensive Cancer Center and President, Atrium Health Levine Cancer. Dr. Mohamed E. Salem, Associate Professor, Gastrointestinal Medical Oncologist Atrium Health Wake Forest Baptist Comprehensive Cancer Center said: “Being part of WIN provides opportunities to advance precision oncology faster, develop novel trials and research programs, and provide more options for patients.”

View the full article here: Download pdf
September 19, 2024 - American Cancer Society and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium join forces to advance innovative cancer research.
September 19, 2024 - American Cancer Society and Worldwide Innovative Network (WIN) in personalized cancer medicine consortium join forces to advance innovative cancer research.

“By joining the global network of WIN, American Cancer Society is expecting to increase its global reach and to help improve cancer outcomes across the world,” said Dr. William L. Dahut, Chief Scientific Officer of the American Cancer Society (ACS).

“We are extremely proud to welcome the ACS to WIN,” said Dr. Wafik S. El-Deiry, Chair of WIN Consortium, Director of the Legorreta Cancer Center, Associate Dean for Oncologic Sciences at The Warren Alpert Medical School, Brown University, and ACS Research Professor “For more than 10 decades, the American Cancer Society has been dedicated to pursuing better outcomes for every cancer, every life in the USA. It’s mission has been to improve the lives of people with cancer and their families through advocacy, research, and patient support, to ensure everyone has an opportunity to prevent, detect, treat, and survive cancer. As the WIN Consortium continues to develop and implement the next generation of Precision Oncology trials with attention to equity, working with ACS provides an exciting path to innovate and demonstrate ways for how patients with cancer will be managed in the next several decades. In this regard, the ACS is a major stakeholder and wonderful partner to work with.”

“The collaboration will look at amplifying and promoting the ACS’s and the WIN Consortium’s impact in advancing Precision Oncology to support their respective overarching missions, that include facilitating translation of discoveries in cancer prevention, therapeutics, and biomarkers as they relate to screening, prediction of or association with therapeutic benefit. This includes AI algorithm-driven therapeutic IND-studies at a growing global footprint of sites. We look forward to increasing access to innovative precision interventions in global communities through scientific approaches and patient navigation. We look forward to working collaboratively to facilitate goals of the emerging ACS-HBCU-Cancer Trials Consortium through biomarker and genomic/AI-based studies in cancer precision therapeutics. Addressing the global burden of cancer through new therapeutics targeting virally-associated cancers, precancerous conditions, rare cancers, cancers from specific tissue origins or tissue agnostic trials are other opportunities of mutual interest between ACS and WIN. We think that partnering between ACS and WIN will foster greater collaboration with academia, pharma companies and foundations in precision oncology research while enhancing networking opportunities and collaborations with ACS-funded researchers.” said Dr. William L. Dahut.

“With so many patients and families affected by cancer, waiting, and hoping for effective cures and treatments, siloed research gets in the way of innovation. WIN was the first consortium that assembled all stakeholders of cancer care, from academia, industry, and patient advocates to work together across the globe. It was also the first organization to launch a N-of-One study using transcriptomics in addition to genomics to inform therapeutic choice in the WINTHER study. WIN offers a platform to launch compelling precision oncology and early diagnosis studies internationally building upon its experience in genomics and transcriptomics. It is a great honor to welcome such a leading cancer-fighting organization in the USA as American Cancer Society” said Dr Razelle Kurzrock, Chief Medical Officer of WIN, Professor of Medicine, Associate Director Clinical Research, MCW Cancer Center and Linda T. & John A. Mellowes of Precision Oncology.

View the full article here: Download pdf
Abu Dhabi's WIN Symposium gathers oncology leaders Gulf Today Newspaper March 02, 2024
Abu Dhabi's WIN Symposium gathers oncology leaders
Gulf Today Newspaper
Magzter
March 02, 2024

ABU DHABI: The WIN Symposium 2024, a landmark event in precision oncology, has officially commenced in Abu Dhabi, marking a significant collaboration between the Worldwide Innovative Network (WIN) Consortium and Burjeel Holdings.

This two-day annual global congress of the WIN Consortium brings together over 500 physicians, researchers, and scientists in the field from 30 countries to explore the latest advancements in precision oncology, with the ultimate goal of improving cancer patient care and outcomes worldwide.

Under the theme “Precision and Molecular Oncology: Caring for Patients and Future Generations”, the congress kicked off with a grand opening featuring 2018 Nobel Laureate, Prof. James Allison, Regental Professor and Chair of the Department of Immunology at the MD Anderson Cancer Center (USA), whose groundbreaking work has revolutionised cancer immunotherapy.

In his keynote lecture, Prof. Allison presented the latest research on how immunotherapy works and the way in which treatments can be improved, tailored and combined so that they are more effective and safe to give to patients with various types of cancer.

On the sidelines of the event, Prof. Allison said, “We are excited to be here and hear about what is happening in the UAE. We are impressed by the infrastructure being built for the development of patient care and cancer treatment, particularly in precision oncology, genomic medicine, and immunotherapy. The future is already here in terms of collaboration with various groups, including this planning infrastructure and building medical systems in Abu Dhabi, especially in clinical trials and the testing of new drugs.”

The WIN Consortium, a non-profit association headquartered in France, unites 31 world-class academic medical centres, healthcare industries, research organisations, and patient advocacy groups from 18 countries, aligned to launch cancer trials using omic platforms to bolster precision oncology across the world.

BMC - Burjeel Medical City, the flagship facility of Burjeel Holdings is the first and only member from the UAE and GCC.

Abu Dhabi was selected as the city to host this year's congress, marking its inaugural occurrence outside of its traditional European venue. This decision reflects the international scientific community's trust in the UAE's vision and capabilities in advancing precision oncology.

View the various news articles here: Download pdf